This is my brain! I made it, and then I made this sculpt and printed it.
Supports are needed, and I highly recommend putting a large solid shape inside to fill the tiny gaps, and then a medium sized void inside that, to reduce the weight, printing time, and filament cost.
You generally have the right to ask for a copy of the files from your own MRI scan.
To turn the MRI dicom files into a 3d print, I followed this youtube video