Enzyme Model with Inhibition & Storage

🧬 Enzyme Model for Illustrating Enzyme Reactions and Inhibitions (Biology)

This 3D-printable **enzyme model** was specially developed for **biology education** and is ideal for clearly explaining **enzyme reactions**, **substrate-product conversions**, as well as **competitive and allosteric inhibition**.
Through modular components, magnetic connections, and an integrated storage mechanism, complex biochemical processes can be presented tangibly and understandably.

🧩 Model Components

🟢 Enzyme

• Large enzyme with:
  • **Active site**
  • **Allosteric site**
• All other components are precisely matched to these two sites
• Integrated **internal storage space**:
  • Side hole + internal cavity
  • Serves to store all loose parts
  • Ideal for everyday school use (no loss of individual parts)

🔷 Substrate & Products

• **Substrate**, which can be bound in the active site
• The substrate can be **split into two products**
• Additionally included:
  • **Water molecule (H₂O)**
  • The two partial molecules each react with water → **product formation**
• This allows a **hydrolytic enzyme reaction** to be realistically represented.

🚫 Competitive Inhibition

• **Two competitive inhibitors**
• Fit **identically in shape into the active site**
• Block substrate binding
• Ideal for explaining:
  • Competition between substrate and inhibitor
  • Concentration dependence of competitive inhibition

🔴 Allosteric Inhibition

• **Allosteric inhibitor**, which:
  • Does not bind in the active site
  • But at the **allosteric site**
• Additionally included:
  • **Two adapters**
  • These change the **shape of the active site** after docking
• Thus it can be clearly shown:
  • That the substrate **no longer fits**
  • Although the active site itself is not blocked
• Perfect for explaining the **conformational change** of an enzyme

🧲 Magnet System

• **All parts contain holes for neodymium magnets (8 × 3 mm)**
• The magnets allow:
  • Stable hold
  • At the same time easy detachment of the components
• ⚠ **IMPORTANT – Pay attention to polarity!**
  • Magnets must be inserted with **correct polarity**
  • Incorrect polarity can lead to:
    • Parts repelling each other
    • The reaction sequence can no longer be correctly represented
• Tip: Test and mark all magnets before gluing

📏 Scaling & Printing Notes

• ❌ **Scaling is not recommended**
  • Magnet holes are precisely designed for 8 × 3 mm
  • When scaling:
    • Magnets no longer fit
    • Function suffers significantly
• The model is optimized for **didactic use**, not for mechanical load

🎓 Educational Value

Among other things, this model can explain:

• Enzyme-substrate complex
• Product formation
• Hydrolysis
• Competitive inhibition
• Allosteric inhibition
• Structure-function relationships
• Storage and organization of biological models

Ideal for:

• Lessons
• Presentations
• Exams
• Learning stations
• Student experiments

📦 Organization & Transport

Thanks to the integrated **storage system within the enzyme itself**, you can:

• All individual parts can be safely stored
• The complete model can be compactly transported
• No additional boxes are needed

Have fun printing, assembling, and teaching!

 

 

The texts can also be changed to English if needed. You can do this yourself via the attached .f3d (Fusion 360) file. You are welcome to send me a direct message so I can do this

 

 

 The model at a glance

 

You can also print the enzyme in a silk filament to represent the amino acid chains of the tertiary structure

 

 

 

 

Of course 👍
Here is **a suitable English heading (≤ 50 characters)** and then the **fully translated, detailed description** for MakerWorld.

🧬 **Enzyme Model with Inhibition & Storage**

(42 characters)

🧬 Educational Enzyme Model for Biology

This 3D-printable **enzyme model** was designed specifically for **biology education** and classroom use. It allows students to **physically simulate enzyme reactions**, product formation, and different types of enzyme inhibition.
Thanks to its **modular design, magnetic connections, and integrated storage**, complex biochemical processes become tangible, interactive, and easy to understand.

🧩 Model Components

🟢 Enzyme

• Large enzyme body featuring:
  • **Active site**
  • **Allosteric site**
• All additional components are precisely matched to these two binding sites
• Integrated **internal storage system**:
  • A hole in the side wall combined with a hollow internal chamber
  • Allows all loose parts to be stored inside the enzyme
  • Ideal for classroom use and transport, preventing loss of parts

🔷 Substrate & Products

• **Substrate molecule** that fits into the active site
• The substrate can be **split into two product molecules**
• Included:
  • **Water molecule (H₂O)**
  • Each substrate fragment reacts with water to form a **product**
• This allows a clear demonstration of a **hydrolytic enzyme reaction**

🚫 Competitive Inhibition

• **Two competitive inhibitors**
• Shape-matched to the **active site**
• Block substrate binding by competing for the same binding pocket
• Perfect for explaining:
  • Competition between substrate and inhibitor
  • Concentration-dependent inhibition effects

🔴 Allosteric Inhibition

• **Allosteric inhibitor** that:
  • Does **not** bind to the active site
  • Instead binds to the **allosteric site**
• Includes:
  • **Two adapter parts**
  • These adapters change the **shape of the active site** after binding
• This clearly demonstrates:
  • How substrate binding is prevented
  • Even though the active site itself is not directly blocked
• Ideal for explaining **enzyme conformational changes**

🧲 Magnetic System

• **All parts include holes for 8 × 3 mm neodymium magnets**
• Magnets allow:
  • Secure connections
  • Easy assembly and disassembly
• ⚠ **IMPORTANT – Magnet polarity matters!**
  • Magnets must be inserted with correct polarity
  • Incorrect polarity may cause:
    • Parts to repel each other
    • The model to function improperly
• Tip: Test and mark magnet polarity before gluing

📏 Scaling & Printing Notes

• ❌ **Scaling is not recommended**
  • Magnet holes are precisely designed for 8 × 3 mm magnets
  • Scaling may cause:
    • Poor magnet fit
    • Reduced functionality
• Optimized for **educational demonstration**, not mechanical load

🎓 Educational Value

This model can be used to demonstrate:

• Enzyme–substrate complex formation
• Product formation
• Hydrolysis reactions
• Competitive inhibition
• Allosteric inhibition
• Structure–function relationships of enzymes

Perfect for:

• Biology classes
• Presentations
• Exams and oral explanations
• Learning stations
• Interactive demonstrations

📦 Storage & Transport

Thanks to the **built-in storage inside the enzyme**, all parts:

• Can be stored safely inside the model
• Are easy to transport
• Require no additional containers